Vitamin

Pyridoxine

Prepared by the ezGLP team. Sources last checked September 5, 2026.

Also known as Vitamin B6, Pyridoxine hydrochloride

Routes represented in the knowledgebase: Oral / Subcutaneous (SubQ).

Educational overview

Oral supplement and prescription injection; chronic high exposure can cause sensory neuropathy.

Category: Vitamin
Routes represented: Oral / Subcutaneous (SubQ)
Storage context: Follow the product or pharmacy label; requirements vary by route and formulation.

Authoritative overview

Published literature

No validated PubMed or DOI link is currently curated for this entry.

Safety evidence

Common or reported: nausea, heartburn, photosensitivity.

Serious or important: progressive sensory neuropathy and ataxia with chronic high supplemental doses.

Safety evidence source

Interaction evidence

These are general, pairwise evidence notes. Green identifies the potential-synergy category, while Lv3/Lv2/Lv1 communicates evidence strength; it does not guarantee benefit or cancel a safety warning.

With levodopa without carbidopa

Safety flag

Pyridoxine can increase peripheral levodopa metabolism and reduce its therapeutic effect.

Interaction evidence source

Summarised from published literature for reference only, with citations to the source. Evidence is graded as reported and is not a recommendation to combine, dose, or use any compound.

For personal tracking and education only. Not medical advice, diagnosis, or treatment, and not a medical device. Peptides may be prescription-only or unapproved where you live — consult a licensed healthcare professional.