With tetracycline or fluoroquinolone antibiotics
Oral magnesium can bind these antibiotics and reduce absorption of both products.
Interaction evidence sourceMineral
Prepared by the ezGLP team. Sources last checked .
Also known as Magnesium glycinate, Magnesium citrate, Magnesium oxide
Routes represented in the knowledgebase: Oral.
Oral salts differ in absorption and tolerability; parenteral magnesium is a monitored prescription treatment, especially in renal impairment.
No validated PubMed or DOI link is currently curated for this entry.
Common or reported: diarrhea, nausea, abdominal cramping.
Serious or important: hypotension, respiratory difficulty, arrhythmia, or cardiac arrest with severe hypermagnesemia.
Severe toxicity is especially relevant with renal failure or parenteral exposure.
Safety evidence sourceThese are general, pairwise evidence notes. Green identifies the potential-synergy category, while Lv3/Lv2/Lv1 communicates evidence strength; it does not guarantee benefit or cancel a safety warning.
Oral magnesium can bind these antibiotics and reduce absorption of both products.
Interaction evidence sourceMagnesium-containing oral products can reduce levothyroxine absorption.
Interaction evidence sourceA randomized human trial found magnesium plus vitamin D increased serum vitamin D status more than vitamin D alone.
Interaction evidence sourceRelated trial analysisNIH magnesium overviewSummarised from published literature for reference only, with citations to the source. Evidence is graded as reported and is not a recommendation to combine, dose, or use any compound.
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